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How Many Units of Botox for Armpits

Dr. Ludwig Allegra

December 3, 2025

Underarm sweating shouldn’t decide what you wear or how you move throughout your day. Yet for those with excessive sweating, every handshake, presentation, or social gathering becomes a source of anxiety. Light clothing becomes your uniform, and you plan your entire wardrobe around hiding sweat stains. The worst part? Prescription antiperspirants often fail to deliver the relief you desperately need.

Botox injections offer a proven medical solution for excessive armpit sweating, providing months of relief from hyperhidrosis. The question most patients ask before their first appointment is straightforward: how many units of Botox do you actually need for the armpits? Let’s understand below.

Understanding the Standard Botox Dosage

When treating underarm sweating with Botox, the dosage varies depending on individual needs. The typical range is 50-100 units per armpit, with most treatment sessions using about 100 units total for both underarms. This amount has proven effective for the majority of patients dealing with axillary hyperhidrosis.

Your provider determines the precise number of units based on several key factors. The severity of your sweating plays the most significant role. Someone with mild hyperhidrosis might respond well to just 40 units per side, while severe cases often require 60-75 units per armpit to achieve noticeable results. The size of your treatment area matters too. If you have a larger underarm area, you’ll naturally need more units to ensure complete coverage across all the active sweat glands.

Previous treatment history also influences dosing decisions. If you’ve received Botox for underarm sweating before, your provider will look at how long those results lasted and adjust accordingly. Some patients find they can use fewer units after multiple treatments, while others maintain the exact dosage for consistent results.

The Science Behind Botox for Sweating

Understanding how Botox actually works helps explain why the dosage matters so much. Botox contains botulinum toxin, which temporarily blocks nerve signals that activate your sweat glands. Specifically, it prevents the release of acetylcholine, the chemical messenger that triggers sweating.

When injected into your underarms, Botox creates a substantial reduction in sweat production in those treated areas. The beauty of this approach is its precision. Your body continues to regulate temperature normally through sweating in other regions, but your underarms stay remarkably dry. This targeted treatment means you get relief exactly where you need it without affecting your body’s overall cooling system.

What Happens During Your Treatment

The actual treatment process is straightforward and relatively quick. Your appointment typically takes 20-30 minutes from start to finish. Your provider begins by marking injection sites across your underarm area, creating a grid pattern to ensure even coverage. Then comes the injection phase, where you’ll receive 15 to 20 small injections per armpit, strategically placed to cover all sweat-producing areas.

Most patients describe the discomfort as minimal, rating it around 2-3 on a 10-point scale. The needles used are very fine, similar to those used for other cosmetic injections. If you’re concerned about pain, numbing cream can be applied beforehand to make the experience even more comfortable.

The best part? There’s essentially no downtime. You can resume most normal activities immediately after your appointment. The only real restriction is avoiding intense exercise for the first 24 hours post-treatment. Light activities are perfectly fine right away.

Timeline for Results

Patience pays off with Botox for underarm sweating, though you won’t need much of it. Most patients start noticing results within 3-5 days after their treatment session. The full effect develops over about two weeks, at which point you’ll experience maximum sweat reduction.

The duration of results varies from person to person, but most patients enjoy dry underarms for 4-6 months. Some lucky individuals see results lasting up to a year. When you do notice sweating returning, it’s simply time for your next treatment session. Many patients find that with regular treatments, the duration between appointments can actually extend over time.

Safety and Side Effects to Expect

Botox for underarm sweating has been used successfully for over two decades, building an extensive safety record. The most common side effects are minor and temporary. You might experience some discomfort at the injection sites, minor bruising or swelling, mild headaches in some cases, or brief muscle weakness near the injection areas. These effects typically resolve within a few days.

Rare complications can include compensatory sweating in other body areas, though this is uncommon. Allergic reactions are extremely rare. When administered by an experienced provider who understands proper injection techniques and dosing, Botox for the armpits is considered very safe.

Is Botox Right for Your Underarm Sweating?

The ideal candidate for Botox armpit treatment has tried prescription antiperspirants without adequate success and experiences daily disruption from excessive sweating. You should be at least 18 years old, have no neuromuscular disorders, and not be pregnant or breastfeeding.

The treatment works particularly well for people whose sweating is localized primarily to the underarms rather than being a whole-body issue. Suppose you find yourself constantly worrying about underarm sweat stains, changing clothes multiple times daily, or avoiding certain social or professional situations because of sweating concerns. In that case, Botox offers a practical solution worth exploring.

Take Control of Your Underarm Sweating

Living with excessive underarm sweating doesn’t have to be your reality. Northwest Face & Body specializes in Botox treatments for hyperhidrosis, customizing the exact number of units to match your individual needs and sweating severity. Our experienced providers understand the nuances of proper dosing and injection techniques that make the difference between adequate results and truly life-changing sweat reduction. Don’t let another day go by worrying about sweat stains and embarrassment. Contact Northwest Face & Body today to schedule your consultation and discover how the right Botox dosage can eliminate your underarm sweating concerns for good.

Read more:

Understanding the Difference Between Botox and Fillers

Botox As A Confidence Booster: 5 Psychological Pros

The Unexpected Change: What Happens When Botox Fades After 2 Weeks?

ABOUT THE AUTHOR

Dr. Ludwig Allegra

Dr. Ludwig Allegra has provided Bellevue, Kirkland, and the surrounding areas with premier plastic surgery procedures for over two decades.